SCHEMBL8996450

SCHEMBL8996450

CC(O)C1CC2CCC1CC2

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 1/20 0.32
GBA1 P04062 1/20 0.31
KMT2A Q03164 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14646057 0.88 HPGD (0.47) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL3345713 0.88 HPGD (0.47) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL5246106 0.81 HPGD (0.42) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL3001955 0.79 LMNA (0.35) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL26371671 0.75 HPGD (0.33) HPGDLMNASMN1; SMN2KMT2AALDH1A1
SCHEMBL22088469 0.75 LMNA (0.33) HPGDLMNASMN1; SMN2
SCHEMBL21665549 0.75 MEN1 (0.33) HPGDLMNASMN1; SMN2KMT2AMEN1
SCHEMBL11612629 0.72 HPGD (0.42) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL24170500 0.71 HPGD (0.42) HPGDLMNASMN1; SMN2POLBKMT2A
SCHEMBL14561043 0.70 HPGD (0.45) HPGDLMNASMN1; SMN2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5422027-A Drive fluid for rotational elements having a torque transmission relationship comprising a bicyclooctane; low viscosity; broad temperature range; automobile transmissions IDEMITSU KOSAN CO., LTD. (JP) 1995-06-06 US claimed
EP-0508292-B1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN CO (JP) 1996-08-28 EP disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed