⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24515479 | 0.92 | — | — | |
| SCHEMBL5414735 | 0.85 | — | — | |
| SCHEMBL24385117 | 0.83 | — | — | |
| Water SCHEMBL10632239 | 0.82 | — | — | |
| SCHEMBL24448939 | 0.77 | MMP8 (0.33) | — | |
| SCHEMBL25111360 | 0.75 | — | — | |
| SCHEMBL18948682 | 0.75 | — | — | |
| SCHEMBL3687892 | 0.74 | USP2 (0.30) | — | |
| SCHEMBL11232698 | 0.74 | CETP (0.33) | — | |
| SCHEMBL13314619 | 0.74 | PIK3CD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231778-A1 | CORONAVIRUS PROTEASE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |
| EP-0508292-B1 | Traction drive fluid, process for producing the same and bicyclo octane compound | IDEMITSU KOSAN CO (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5422027-A | Drive fluid for rotational elements having a torque transmission relationship comprising a bicyclooctane; low viscosity; broad temperature range; automobile transmissions | IDEMITSU KOSAN CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0508292-A1 | Traction drive fluid, process for producing the same and bicyclo octane compound | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-10-14 | — | — | EP | disclosed |