Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412243 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412225 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412204 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL8996607 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412274 | 0.78 | MAPT (0.58) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412186 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412213 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL8996591 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412224 | 0.76 | FNTA (0.33) | ALDH1A1MAPTHSD17B10MAPK1TP53 | |
| SCHEMBL9412223 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MAPTHSD17B10MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484934-A | FUNGICIDE, WOOD PRESERVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0604978-A1 | Isothiazole derivatives, a process for production thereof and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0578246-A1 | Isothiazole derivatives and processes for preparing the same as well as termite controlling agents comprising the same as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |