Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 8/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.34 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412247 | 0.80 | RECQL (0.36) | ALDH1A1MAPK1MAPTHSD17B10TSHR | |
| SCHEMBL8996607 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HTTMAPK1MAPTHSD17B10 | |
| SCHEMBL8996632 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HTTMAPK1MAPTHSD17B10 | |
| SCHEMBL8996641 | 0.75 | RECQL (0.33) | MAPK1MAPTHSD17B10TSHRTP53 | |
| SCHEMBL5638835 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HTTMAPK1MAPTHSD17B10 | |
| SCHEMBL5150632 | 0.75 | RECQL (0.38) | ALDH1A1MAPK1MAPTHSD17B10TSHR | |
| SCHEMBL11563951 | 0.75 | RECQL (0.46) | ALDH1A1HTTMAPK1MAPTTSHR | |
| SCHEMBL5639428 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HTTMAPK1MAPTHSD17B10 | |
| SCHEMBL9412202 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HTTMAPK1MAPTHSD17B10 | |
| SCHEMBL15570566 | 0.73 | RECQL (0.41) | ALDH1A1MAPK1MAPTTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484934-A | FUNGICIDE, WOOD PRESERVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0604978-A1 | Isothiazole derivatives, a process for production thereof and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |