Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 2/20 | 0.70 |
| ▸ | SRD5A1 | P18405 | 10/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725551 | 0.88 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8723340 | 0.88 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8723334 | 0.88 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8723337 | 0.88 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8725548 | 0.88 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8725556 | 0.88 | HSD17B7 (0.57) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8065264 | 0.87 | HSD17B7 (0.64) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8065261 | 0.87 | HSD17B7 (0.64) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8075536 | 0.86 | HSD17B7 (0.58) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8724745 | 0.86 | SRD5A1 (0.57) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724592-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO. INC. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011254-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO., INC. (US) | 1995-04-27 | — | — | WO | disclosed |