Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B7 | P56937 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 13/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996737 | 0.92 | SRD5A1 (0.38) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8996741 | 0.92 | SRD5A1 (0.38) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8996721 | 0.81 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8996714 | 0.81 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL8996698 | 0.81 | SRD5A1 (0.34) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8522969 | 0.81 | SRD5A1 (0.34) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8996745 | 0.80 | SRD5A1 (0.34) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8996742 | 0.80 | SRD5A1 (0.34) | HSD17B7SRD5A1SRD5A2 | |
| SCHEMBL8996747 | 0.80 | SRD5A1 (0.38) | SRD5A1SRD5A2 | |
| SCHEMBL8996732 | 0.80 | SRD5A1 (0.38) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724592-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO. INC. (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011254-A1 | 16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS | MERCK & CO., INC. (US) | 1995-04-27 | — | — | WO | claimed |