SCHEMBL8997093

SCHEMBL8997093

Fc1cccc2c1-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1cccc(F)c41)-c1cccc(F)c1-3)c1c(F)cccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 5/20 0.36
JAK2 O60674 1/20 0.35
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
GBA1 P04062 2/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
FEN1 P39748 1/20 0.31
PARP1 P09874 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TYMS P04818 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8996991 1.00 PTGES (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL170655 0.88 MEN1 (0.37) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL28980882 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL28980881 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL4343033 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL9101740 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL5148510 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL5148520 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL5826832 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB
SCHEMBL5148506 0.87 MEN1 (0.36) PTGESJAK2GSK3AGSK3BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460615-B1 Electrophotographic recording elements containing a combination of titanyl phthalocyanine-type pigments EASTMAN KODAK CO (US) 1996-09-04 EP disclosed
US-5112711-A Photoconductive material dispersed in a binder EASTMAN KODAK COMPANY (US) 1992-05-12 US disclosed
EP-0460615-A1 Electrophotographic recording elements containing a combination of titanyl phthalocyanine-type pigments EASTMAN KODAK COMPANY (US) 1991-12-11 EP disclosed