SCHEMBL8997133

SCHEMBL8997133

CC(C)=CCC/C(C)=C/Cc1cccc(C/C=C(\C)CCC=C(C)C)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.54
MAOB P27338 3/20 0.51
OSBP P22059 1/20 0.51
BACE1 P56817 2/20 0.50
PPARG P37231 2/20 0.50
PPARA Q07869 2/20 0.50
APP P05067 2/20 0.50
VKORC1 Q9BQB6 1/20 0.50
PTPN1 P18031 1/20 0.50
KMT2A Q03164 1/20 0.48
PTGS1 P23219 2/20 0.48
PTGES O14684 1/20 0.48
ALOX5 P09917 1/20 0.48
PTGS2 P35354 1/20 0.48
PGR P06401 1/20 0.47
HTR1A P08908 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
MAPT P10636 1/20 0.47
PDE4A P27815 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8997136 1.00 ACHE (0.54) ACHEMAOBOSBPBACE1PPARG
SCHEMBL23169748 0.92 ACHE (0.57) ACHEMAOBOSBPBACE1PPARG
SCHEMBL31611507 0.91 ACHE (0.56) ACHEMAOBOSBPBACE1PPARG
SCHEMBL15970519 0.91 ACHE (0.56) ACHEMAOBOSBPBACE1PPARG
SCHEMBL30555857 0.91 ACHE (0.56) ACHEMAOBOSBPBACE1PPARG
SCHEMBL8850727 0.91 MAOB (0.54) ACHEMAOBOSBPBACE1PPARG
SCHEMBL14248440 0.91 ACHE (0.56) ACHEMAOBOSBPBACE1PPARG
SCHEMBL8850717 0.91 MAOB (0.54) ACHEMAOBOSBPBACE1PPARG
SCHEMBL15970483 0.91 ACHE (0.56) ACHEMAOBOSBPBACE1PPARG
SCHEMBL15970484 0.91 ACHE (0.56) ACHEMAOBOSBPBACE1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530442-B1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEM CORP (JP) 1996-09-04 EP disclosed
US-5266673-A Compatibilizer for polymer blends and alloys MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-30 US disclosed
EP-0530442-A1 Process for producing a hydroxy-substituted poly (phenylene ether) resin MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-10 EP disclosed