SCHEMBL8997140

SCHEMBL8997140

C=C(CCl)C(=O)C(=C)CCl

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163575 0.76
SCHEMBL7628529 0.76
SCHEMBL14054567 0.73 TSHR (0.30) TSHRALDH1A1
SCHEMBL2057851 0.73
SCHEMBL14054332 0.69 ALDH1A1 (0.32) TSHRALDH1A1TDP1
SCHEMBL8406042 0.69
SCHEMBL27829890 0.69
SCHEMBL14079977 0.67
SCHEMBL5350646 0.67 OR51E2 (0.32)
SCHEMBL514403 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538640-B1 Acrylic copolymer elastomer and vulcanizable composition containing same NIPPON ZEON CO (JP) 1996-09-04 EP disclosed
US-5280080-A Copolymerizing mixture of alkyl acrylates NIPPON ZEON CO., LTD. (JP) 1994-01-18 US disclosed
US-5216101-A Heat, cold, ozone and oil resistance; useful for gaskets, hoses, conveyor belts, packing and bearing or oil seals NIPPON ZEON CO., LTD. (JP) 1993-06-01 US disclosed
EP-0538640-A1 Acrylic copolymer elastomer and vulcanizable composition containing same NIPPON ZEON CO., LTD. (JP) 1993-04-28 EP disclosed
US-4094832-A Vinylic group containing dextran derivative gel for use in electrophoretic separation processes PHARMACIA FINE CHEMICALS AB (SW) 1978-06-13 US disclosed