Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789628 | 0.95 | GRM2 (0.36) | GRM2TP53POLBMAPTKDM1A | |
| SCHEMBL8997251 | 0.95 | GRM2 (0.43) | GRM2TP53POLBMAPTKDM1A | |
| SCHEMBL9556153 | 0.94 | TP53 (0.39) | GRM2TP53POLBMAPTCHRM1 | |
| SCHEMBL9556149 | 0.94 | TP53 (0.39) | GRM2TP53POLBMAPTCHRM1 | |
| SCHEMBL7782379 | 0.93 | GRM2 (0.34) | GRM2TP53POLBMAPTKDM1A | |
| SCHEMBL7782373 | 0.93 | GRM2 (0.34) | GRM2TP53POLBMAPTKDM1A | |
| SCHEMBL7774584 | 0.92 | GRM2 (0.34) | GRM2TP53POLBMAPTKDM1A | |
| SCHEMBL7774588 | 0.92 | GRM2 (0.34) | GRM2TP53POLBMAPTKDM1A | |
| SCHEMBL16789629 | 0.91 | GRM2 (0.40) | GRM2KDM1ARCOR1CYP1A2 | |
| SCHEMBL8997307 | 0.90 | KDM1A (0.36) | GRM2MAPTKDM1ARCOR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471831-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5389289-A | Chemical and heat resistance | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0471831-A1 | LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991013947-A2 | LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-09-19 | — | — | WO | disclosed |