Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789627 | 0.95 | MEN1 (0.35) | KDM1ARCOR1GRM2MEN1KMT2A | |
| SCHEMBL9556539 | 0.94 | CYP2C9 (0.38) | KDM1ARCOR1GRM2CYP2C9MEN1 | |
| SCHEMBL9556542 | 0.94 | CYP2C9 (0.38) | KDM1ARCOR1GRM2CYP2C9MEN1 | |
| SCHEMBL7782319 | 0.92 | KDM1A (0.32) | KDM1ARCOR1GRM2SLC6A2HTR2A | |
| SCHEMBL7782316 | 0.92 | KDM1A (0.32) | KDM1ARCOR1GRM2SLC6A2HTR2A | |
| SCHEMBL7779343 | 0.91 | KDM1A (0.31) | KDM1ARCOR1GRM2 | |
| SCHEMBL7779349 | 0.91 | KDM1A (0.31) | KDM1ARCOR1GRM2 | |
| SCHEMBL8997203 | 0.90 | GRM2 (0.38) | KDM1ARCOR1GRM2SLC6A2SLC6A4 | |
| SCHEMBL8997251 | 0.89 | GRM2 (0.43) | KDM1ARCOR1GRM2ALDH1A1MAPT | |
| SCHEMBL16789628 | 0.86 | GRM2 (0.36) | KDM1ARCOR1GRM2CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471831-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5389289-A | Chemical and heat resistance | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0471831-A1 | LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991013947-A2 | LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-09-19 | — | — | WO | disclosed |