Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347904 | 0.98 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL8095323 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9224351 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9224377 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9224357 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL8095319 | 0.95 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9227020 | 0.92 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9227023 | 0.92 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9351881 | 0.90 | HTR2C (0.51) | ALDH1A1LMNAMAPTCYP2C9HTR2C | |
| SCHEMBL9227025 | 0.90 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTCYP2C9HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471831-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5389289-A | Chemical and heat resistance | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| EP-0471831-A1 | LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991013947-A2 | LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-09-19 | — | — | WO | disclosed |
| US-4871469-A | TRIFLUOROTOLUENE DERIVATIVES | BESCRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |