Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997283 | 0.95 | GRM2 (0.43) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7778850 | 0.93 | MAPK1 (0.37) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7778853 | 0.93 | MAPK1 (0.37) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7774307 | 0.92 | MAPK1 (0.36) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7774310 | 0.92 | MAPK1 (0.36) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL8997289 | 0.90 | SLC6A3 (0.43) | MAPK1DRD2SLC6A3GRM2KDM1A | |
| SCHEMBL7774631 | 0.89 | GRM2 (0.39) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7774626 | 0.89 | GRM2 (0.39) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7781470 | 0.87 | GRM2 (0.38) | MAPK1DRD2SLC6A3GRM2KDM4E | |
| SCHEMBL7781466 | 0.87 | GRM2 (0.38) | MAPK1DRD2SLC6A3GRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471831-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5389289-A | Chemical and heat resistance | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0471831-A1 | LIQUID CRYSTALLINE MEDIUM. | MERCK PATENT GMBH (DE) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991013947-A2 | LIQUID CRYSTALLINE MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-09-19 | — | — | WO | disclosed |