Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP4 | P49662 | 1/20 | 0.37 |
| ▸ | CASP5 | P51878 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644295 | 0.75 | UHRF1 (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16915857 | 0.75 | UHRF1 (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24697999 | 0.69 | KDM4E (0.49) | SMN1; SMN2HTR2CMEN1KMT2AMAPK1 | |
| SCHEMBL13131427 | 0.67 | HRH1 (0.38) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4429104 | 0.64 | CHRM3 (1.00) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12085258 | 0.64 | UHRF1 (0.32) | UHRF1 | |
| SCHEMBL18998118 | 0.63 | KDM4E (0.46) | SMN1; SMN2TDP1UHRF1KMT2ACYP1A2 | |
| SCHEMBL1975340 | 0.62 | HRH1 (0.70) | HRH1SMN1; SMN2USP2TDP1CASP1 | |
| SCHEMBL14078176 | 0.61 | UHRF1 (0.50) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11208162 | 0.60 | SMN1; SMN2 (0.71) | HRH1SMN1; SMN2USP2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8092250-A | — | — | None | — | — | JP | disclosed |
| JP-H0892250-A | NEW PYRIDO(2,3-D)PYRIMIDINE DERIVATIVE AND PRODUCTION THEREOF | ASAHI BREWERIES LTD | 1996-04-09 | — | — | JP | disclosed |