Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226273 | 0.84 | MEN1 (1.00) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL2990827 | 0.84 | MEN1 (1.00) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL27834982 | 0.82 | MEN1 (0.94) | MEN1KMT2ALMNAMAPTTSHR | |
| Phosphine SCHEMBL27652671 | 0.82 | MEN1 (0.94) | MEN1KMT2ALMNAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL227522 | 0.82 | MEN1 (0.94) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL335808 | 0.82 | — | — | |
| SCHEMBL28125636 | 0.79 | MEN1 (0.88) | MEN1KMT2ALMNAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL28047633 | 0.79 | MEN1 (0.88) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL12790366 | 0.79 | MEN1 (0.46) | MEN1KMT2ATSHR | |
| Water SCHEMBL28946191 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523303-A | ANTIULCER AND -SECRETORY AGENTS; GASTRIC H+K+ ATPASE INHIBITORS; NONTOXIC; OXIMES DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 1996-06-04 | — | — | US | disclosed |
| EP-0619298-A2 | (Phenylmethylene)-2-(alkyl)-1- omega-(amino)-alkoxyimino -cycloalkane derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |