Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.88 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990827 | 0.94 | MEN1 (1.00) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL226273 | 0.94 | MEN1 (1.00) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL27834982 | 0.91 | MEN1 (0.94) | MEN1KMT2AMAPTLMNATP53 | |
| Hydrochloric Acid SCHEMBL227522 | 0.91 | MEN1 (0.94) | MEN1KMT2AMAPTLMNATP53 | |
| Phosphine SCHEMBL27652671 | 0.91 | MEN1 (0.94) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL28125636 | 0.88 | MEN1 (0.88) | MEN1KMT2AMAPTLMNATP53 | |
| Hydrochloric Acid SCHEMBL8950200 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTLMNATP53 | |
| Tert-Butylamine SCHEMBL9152840 | 0.79 | MEN1 (0.71) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL8997704 | 0.79 | MEN1 (0.71) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL28303603 | 0.78 | MEN1 (0.68) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118083948-A | Resin-based coated asphalt-based hard carbon composite material and preparation method thereof | 河北坤天新能源股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-105347843-A | Water-proofing agent for reinforced concrete structure building | CHUZHOU SIMAITE COMPOSITE MATERIAL CO LTD | 2016-02-24 | — | — | CN | disclosed |