Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TK2 | O00142 | 5/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NT5C | Q8TCD5 | 1/20 | 0.41 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090870 | 0.82 | TK1 (0.72) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3090867 | 0.82 | TK1 (0.72) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL4283383 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL99350 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL5983819 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL1172398 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3066358 | 0.80 | TK1 (0.83) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL4283382 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL21316784 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| Brivudine SCHEMBL13674189 | 0.80 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001326-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-02-07 | — | — | WO | claimed |
| EP-0409575-A1 | Antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-01-23 | — | — | EP | claimed |
| US-5521163-A | TREATMENT OF HERPES VIRUS WITH 1'-DEOXY-5-ETHYL-4'-THIO-BETA URIDINE | UNIVERSITY OF BIRMINGHAM (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0658166-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | THE UNIVERSITY OF BIRMINGHAM (GB) | 1995-06-21 | — | — | EP | disclosed |
| US-5356882-A | Treating herpes virus | UNIVERSITY OF BIRMINGHAM (GB) | 1994-10-18 | — | — | US | disclosed |
| WO-1994005687-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | disclosed |
| WO-1991001326-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-02-07 | — | — | WO | disclosed |