Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ritiometan SCHEMBL867253 | 0.74 | CYP2C19 (0.53) | CYP2D6HIF1ACYP2C19HSD17B10LMNA | |
| SCHEMBL28364242 | 0.72 | — | — | |
| SCHEMBL503348 | 0.71 | CYP2C19 (0.50) | CYP2D6HIF1ACYP2C19TDP1HSD17B10 | |
| SCHEMBL3151822 | 0.70 | — | — | |
| SCHEMBL8187506 | 0.69 | CYP2D6 (0.36) | CYP2D6HIF1ACYP2C19ALKBH5 | |
| SCHEMBL23931412 | 0.68 | BHMT (0.42) | CYP2D6HIF1ACYP2C19TDP1ALOX15 | |
| SCHEMBL2808412 | 0.68 | BHMT (0.42) | CYP2D6HIF1ACYP2C19TDP1ALOX15 | |
| SCHEMBL1578703 | 0.68 | CYP2D6 (0.41) | CYP2D6HIF1ACYP2C19HSD17B10KDM4E | |
| SCHEMBL19492091 | 0.68 | BHMT (0.42) | CYP2D6HIF1ACYP2C19TDP1ALOX15 | |
| SCHEMBL8030361 | 0.67 | CYP2D6 (0.45) | CYP2D6HIF1ACYP2C19HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574117-A | SULFUR COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |