SCHEMBL8998092

SCHEMBL8998092

CCCCC(N)(CCCC)C(O)CC

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.40
TSHR P16473 1/20 0.40
SMPD1 P17405 4/20 0.33
S1PR1 P21453 3/20 0.32
S1PR4 O95977 2/20 0.32
S1PR3 Q99500 2/20 0.32
S1PR5 Q9H228 2/20 0.32
S1PR2 O95136 1/20 0.32
TNNC1 P63316 5/20 0.32
SGPL1 O95470 1/20 0.32
GPR183 P32249 1/20 0.32
CERS2 Q96G23 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8998071 0.93 FDPS (0.42) FDPSTSHRSMPD1S1PR1S1PR4
SCHEMBL5191501 0.84 FDPS (0.39) FDPSSMPD1CA1CA2SPHK1
SCHEMBL2351408 0.84 TSHR (0.39) TSHR
SCHEMBL3856250 0.84 FDPS (0.39) FDPSSMPD1CA1CA2SPHK1
Water SCHEMBL1335120 0.82 FDPS (0.38) FDPSSMPD1CA1CA2SPHK1
SCHEMBL11611964 0.80 SPHK1 (0.45) FDPSSMPD1SPHK1
SCHEMBL18676132 0.80 FDPS (0.43) FDPSTSHRSMPD1S1PR1S1PR4
SCHEMBL6839709 0.79 FDPS (0.35) FDPSCA1CA2SPHK1
SCHEMBL7752435 0.78 FDPS (0.41) FDPSTSHRSMPD1SPHK1
SCHEMBL3798895 0.77 FDPS (0.41) FDPSSMPD1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0519747-B1 Cement admixture and defoaming agent GRACE W R & CO (US) 1996-09-04 EP claimed
EP-0519747-A2 Cement admixture and defoaming agent W.R. Grace & Co.-Conn. (US) 1992-12-23 EP claimed
US-5156679-A Water soluble alkylated alkanolamine salts W. R. GRACE & CO.-CONN. (US) 1992-10-20 US claimed
EP-0519747-B1 Cement admixture and defoaming agent GRACE W R & CO (US) 1996-09-04 EP disclosed
EP-0519747-A2 Cement admixture and defoaming agent W.R. Grace & Co.-Conn. (US) 1992-12-23 EP disclosed
US-5156679-A Water soluble alkylated alkanolamine salts W. R. GRACE & CO.-CONN. (US) 1992-10-20 US disclosed