Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998064 | 0.88 | HCAR2 (0.55) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL2421338 | 0.85 | ATM (0.74) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL9395625 | 0.83 | ATM (0.65) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL6463318 | 0.82 | TSHR (0.85) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| Ethylene SCHEMBL27650794 | 0.81 | ATM (0.91) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| Ethylene SCHEMBL11884689 | 0.81 | ATM (0.91) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| Ethylene SCHEMBL11884679 | 0.81 | ATM (0.91) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL27914900 | 0.81 | TSHR (0.81) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| Methacrylic Acid SCHEMBL11082248 | 0.81 | ATM (0.74) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL28154 | 0.81 | ATM (1.00) | ATMTSHRHPGDHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |