Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543838 | 0.90 | SLC1A1 (0.56) | SLC1A1OR51E2LMNAALDH1A1SLC1A3 | |
| SCHEMBL632316 | 0.83 | FOLH1 (0.48) | SLC1A1OR51E2LMNAALDH1A1TDP1 | |
| SCHEMBL5694983 | 0.83 | SLC1A1 (0.54) | SLC1A1OR51E2LMNAALDH1A1SLC1A3 | |
| SCHEMBL7591996 | 0.83 | LMNA (0.52) | SLC1A1OR51E2LMNAFOLH1 | |
| SCHEMBL28661280 | 0.80 | CHRM1 (0.60) | SLC1A1OR51E2SLC1A3SLC1A2CHRM1 | |
| SCHEMBL27753510 | 0.80 | MME (0.40) | SLC1A1OR51E2LMNAALDH1A1SLC1A3 | |
| SCHEMBL14871742 | 0.78 | GRIK1 (0.44) | SLC1A1SLC1A3SLC1A2FOLH1USP2 | |
| SCHEMBL8062118 | 0.78 | GRIK1 (0.44) | SLC1A1SLC1A3SLC1A2FOLH1USP2 | |
| SCHEMBL17635909 | 0.78 | OR51E2 (0.48) | SLC1A1OR51E2LMNAALDH1A1PDE4A | |
| SCHEMBL851734 | 0.77 | GRIK1 (0.43) | SLC1A1SLC1A3SLC1A2CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725636-A1 | HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM | FHJ SCIENTIFIC, INC. (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995010272-A1 | HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM | FHJ SCIENTIFIC, INC. (US) | 1995-04-20 | — | — | WO | disclosed |