Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118438 | 1.00 | HSD17B10 (0.67) | HSD17B10VCAM1PDE7AKMT2AALDH1A1 | |
| SCHEMBL30962630 | 0.83 | HSD17B10 (0.67) | HSD17B10VCAM1PDE7AKMT2AALDH1A1 | |
| SCHEMBL527809 | 0.83 | HSD17B10 (0.67) | HSD17B10VCAM1PDE7AKMT2AALDH1A1 | |
| SCHEMBL29360183 | 0.80 | HSD17B10 (1.00) | HSD17B10VCAM1PDE7AKMT2AALDH1A1 | |
| SCHEMBL85918 | 0.80 | HSD17B10 (1.00) | HSD17B10VCAM1PDE7AKMT2AALDH1A1 | |
| SCHEMBL30317899 | 0.80 | PTPRC (0.54) | HSD17B10ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL3277269 | 0.80 | PTPRC (0.54) | HSD17B10ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL11050883 | 0.78 | PTPRC (0.57) | HSD17B10KMT2AALDH1A1TDP1CYP3A4 | |
| SCHEMBL4870825 | 0.77 | HSD17B10 (0.69) | HSD17B10VCAM1PDE7AKMT2AALDH1A1 | |
| SCHEMBL1181388 | 0.77 | ALDH1A1 (0.64) | HSD17B10KMT2AALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278932-B1 | Process for preparation of 2-chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide solid forms | SHILPA MEDICARE LIMITED (IN) | 2016-03-08 | — | — | US | claimed |
| US-20160060220-A1 | PROCESS FOR PREPARATION OF 2-CHLORO-N-(4-CHLORO-3-PYRIDIN-2-YLPHENYL)-4-METHYLSULFONYLBENZAMIDE SOLID FORMS | SHILPA MEDICARE LIMITED (IN) | 2016-03-03 | — | — | US | claimed |
| EP-2976326-A2 | PROCESS FOR PREPARATION OF 2-CHLORO-N-(4-CHLORO-3-PYRIDIN-2-YLPHENYL)-4-METHYLSULFONYLBENZAMIDE SOLID FORMS | Shilpa Medicare Limited (IN) | 2016-01-27 | — | — | EP | claimed |
| CN-105218379-A | The synthetic method of the chloro-5-bromaniline of a kind of 3- | GAO DAYUAN | 2016-01-06 | — | — | CN | claimed |
| WO-2014147504-A2 | PROCESS FOR PREPARATION OF 2-CHLORO-N-(4-CHLORO-3-PYRIDIN-2-YLPHENYL)-4-METHYLSULFONYLBENZAMIDE SOLID FORMS | SHILPA MEDICARE LIMITED (IN) | 2014-09-25 | — | — | WO | claimed |
| WO-2026090317-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-3898587-B1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| CN-111566100-B | Pyrimidine compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWING UNIV FREIBURG (DE) | 2022-02-24 | — | — | US | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| US-5990133-A | TREATING CENTRAL NERVOUS SYSTEM DISORDERS SUCH AS ANXIETY OR DEPRESSION | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-11-23 | — | — | US | disclosed |
| EP-0880510-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| CN-1179156-A | Indole derivatives as 5-HT receptor antagonists | SMITHKINE BEECHAM PLC (GB) | 1998-04-15 | — | — | CN | disclosed |
| EP-0808312-A1 | INDOLE DERIVATIVES AS 5-HT RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM PLC (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1997028138-A1 | PROCESS FOR THE PRODUCTION OF 5-HYDROXYOXAZOLIDINONES | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |
| WO-1996023783-A1 | INDOLE DERIVATIVES AS 5-HT RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM PLC (GB) | 1996-08-08 | — | — | WO | disclosed |
| US-4194005-A | Combating arthropods with 4-cyano-4'-[N-(N'-substituted-benzoyl)-ureido]-diphenyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | HSD17B10 4521/4885VCAM1 4799/4885PDE7A 2184/4885 |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | SHH, GLI1, SMO | HSD17B10 4504/4885VCAM1 4796/4885PDE7A 2126/4885 |
| US-20160060220-A1 | PROCESS FOR PREPARATION OF 2-CHLORO-N-(4-CHLORO-3-PYRIDIN-2-YLPHENYL)-4-METHYLSULFONYLBENZAMIDE SOLID FORMS | SKP1, CYP2S1, KDM4A | HSD17B10 3992/4885VCAM1 2296/4885PDE7A 4467/4885 |
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD2 | HSD17B10 1334/4885VCAM1 2006/4885PDE7A 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.