Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999028 | 1.00 | TSHR (0.47) | TSHRALDH1A1ERCC5FEN1CYP2C9 | |
| SCHEMBL8999026 | 1.00 | TSHR (0.47) | TSHRALDH1A1ERCC5FEN1CYP2C9 | |
| SCHEMBL8937476 | 0.81 | KMT2A (0.54) | TSHRALDH1A1P2RX7 | |
| SCHEMBL8937477 | 0.81 | KMT2A (0.54) | TSHRALDH1A1P2RX7 | |
| SCHEMBL8937474 | 0.81 | KMT2A (0.54) | TSHRALDH1A1P2RX7 | |
| SCHEMBL7218671 | 0.75 | ALDH1A1 (0.53) | TSHRALDH1A1ERCC5FEN1PKM | |
| SCHEMBL8297430 | 0.72 | TSHR (0.60) | TSHRALDH1A1ERCC5FEN1CYP2C9 | |
| SCHEMBL8937417 | 0.69 | KMT2A (0.64) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8937423 | 0.69 | KMT2A (0.64) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8937427 | 0.69 | KMT2A (0.64) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556852-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |