Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999123 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1LMNAMEN1NFKB1 | |
| SCHEMBL10620312 | 0.87 | RAB9A (0.49) | KMT2AALDH1A1LMNAMEN1NFKB1 | |
| SCHEMBL24704170 | 0.87 | RAB9A (0.49) | KMT2AALDH1A1LMNAMEN1NFKB1 | |
| SCHEMBL10620307 | 0.87 | RAB9A (0.49) | KMT2AALDH1A1LMNAMEN1NFKB1 | |
| SCHEMBL24704166 | 0.84 | RAB9A (0.50) | KMT2AALDH1A1LMNAMEN1RAB9A | |
| SCHEMBL8999182 | 0.79 | PDE4A (0.60) | KMT2ALMNAMEN1RAB9ANPC1 | |
| SCHEMBL8999173 | 0.79 | PDE4A (0.60) | KMT2ALMNAMEN1RAB9ANPC1 | |
| SCHEMBL4821488 | 0.78 | PDE4A (0.68) | RAB9APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4821491 | 0.78 | PDE4A (0.68) | RAB9APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14189755 | 0.78 | PDE4A (0.55) | KMT2AALDH1A1LMNAMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |