Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166474 | 0.91 | — | — | |
| Acetic Acid Methyl Ester SCHEMBL28972032 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MGAMGAASIMGAM2 | |
| Acetic Acid SCHEMBL7849408 | 0.72 | FFAR3 (0.54) | FFAR3LCKFYNTDP1 | |
| Acetic Acid SCHEMBL3925485 | 0.72 | FFAR3 (0.54) | FFAR3LCKFYNTDP1 | |
| Acetic Acid SCHEMBL30830 | 0.72 | FFAR3 (0.54) | FFAR3LCKFYNTDP1 | |
| Acetic Acid SCHEMBL8437478 | 0.72 | — | — | |
| Acetic Acid SCHEMBL27526532 | 0.71 | — | — | |
| Acetic Acid SCHEMBL26093699 | 0.71 | FFAR3 (0.64) | ALDH1A1FFAR3LCKFYNTDP1 | |
| Acetic Acid SCHEMBL15265007 | 0.71 | FFAR3 (0.64) | ALDH1A1FFAR3LCKFYNMGAM | |
| Acetic Acid SCHEMBL5855458 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510402-A | STABILIZING POLYOLEFINS AND STYRENE COPOLYMERS AGAINST HEAT, OXIDATION AND ACTINIC RADIATION | CIBA-GEIGY CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |