SCHEMBL8999515

SCHEMBL8999515

Cc1cc(Cl)cc(OC(N)=O)c1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.36
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.35
ELANE P08246 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2071865 0.86 MEN1 (0.52) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL19970579 0.86 MEN1 (0.52) KMT2AMEN1MAPTALDH1A1CYP1A2
SCHEMBL16959281 0.82 LMNA (0.53) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL11094550 0.80 HPGD (0.38) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL28362239 0.77 MEN1 (0.44) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL29177324 0.77 MEN1 (0.44) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL27560290 0.77 MEN1 (0.44) KMT2AMEN1
SCHEMBL28959390 0.75 KMT2A (0.45) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL11463871 0.74 RXRB (0.41) KMT2AMEN1MAPTTHRBLMNA
SCHEMBL15654679 0.74 KMT2A (0.41) KMT2AMEN1MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117665154-B Method for detecting voriconazole dextroisomer by adopting reversed phase chromatography 重庆药友制药有限责任公司 2024-07-12 CN claimed
CN-118126011-A Method for chiral resolution of Trolox and Trolox ester compound enantiomer 辽宁大学 2024-06-04 CN claimed
CN-117665154-A Method for detecting voriconazole dextroisomer by adopting reversed phase chromatography 重庆药友制药有限责任公司 2024-03-08 CN claimed
CN-117007727-A High performance liquid chromatography method 上海医药工业研究院有限公司 2023-11-07 CN claimed
CN-114428131-B Detection method for resolving diastereoisomers of glycopyrronium bromide intermediate 山东泰合医药科技有限公司 2023-09-15 CN claimed
CN-116519823-A Method for efficiently separating four pairs of alkaloid enantiomers based on column series technology 云南中烟工业有限责任公司 2023-08-01 CN claimed
CN-116106443-A Method for determining optical isomer of nicotine and application thereof 深圳市真味生物科技有限公司 2023-05-12 CN claimed
CN-115902018-A Detection method of linezolid isomer 江苏晨牌药业集团股份有限公司 2023-04-04 CN claimed
CN-112782333-B HPLC detection method for pitavastatin isopropyl tert-butyl ester diastereoisomer 石家庄四药有限公司 2022-07-12 CN claimed
CN-114689707-A Detection method of acetylcysteine enantiomer 四川汇宇制药股份有限公司 2022-07-01 CN claimed
CN-114509389-A Hesperetin chiral isomer structure identification and separation analysis method 浙江省柑橘研究所 2022-05-17 CN claimed
CN-114428131-A Detection method for resolving diastereoisomer of glycopyrronium bromide intermediate 山东泰合医药科技有限公司 2022-05-03 CN claimed
CN-110376295-B Detection method and application of silodosin enantiomer 北京华氏康源医药科技有限公司 2022-03-18 CN claimed
CN-114200061-A High performance liquid detection method for gingerol component content 泉州海关综合技术服务中心 2022-03-18 CN claimed
CN-114076799-A Method for detecting isomer in brivaracetam injection by using high performance liquid chromatography 扬子江药业集团四川海蓉药业有限公司 2022-02-22 CN claimed
CN-109725073-B Separation and detection method of acetylcysteine enantiomer 湖南华纳大药厂科技开发有限公司 2021-10-15 CN claimed
CN-112782333-A HPLC detection method for pitavastatin isopropyl tert-butyl ester diastereoisomer 石家庄四药有限公司 2021-05-11 CN claimed
CN-107505410-B Method for resolving nateglinide and stereoisomer thereof by high performance liquid chromatography 江苏德源药业股份有限公司 2020-05-08 CN claimed
JP-8231489-A None JP disclosed
JP-H08231489-A NEW ISOCYANATE, DERIVATIVE THEREFROM, AND SEPARATION AGENT DAICEL CHEM IND LTD 1996-09-10 JP disclosed