Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6060568 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL7634128 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL3391859 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL52420 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL2450121 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7628004 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL4184421 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6061039 | 0.97 | HIF1A (0.70) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6060715 | 0.95 | HIF1A (0.74) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL2446042 | 0.95 | HIF1A (0.74) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414160-B1 | Process for preparing advanced epoxy resins | DOW CHEMICAL CO (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0414160-A2 | Process for preparing advanced epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |