Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.51 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2450121 | 1.00 | HIF1A (0.70) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL7634128 | 1.00 | HIF1A (0.70) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL3391859 | 1.00 | HIF1A (0.70) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL4184421 | 1.00 | HIF1A (0.70) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL8999525 | 0.97 | HIF1A (0.67) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL29466951 | 0.97 | HIF1A (0.74) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL2446042 | 0.97 | HIF1A (0.74) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL29438162 | 0.97 | HIF1A (0.74) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL31447355 | 0.97 | HIF1A (0.74) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Iodide SCHEMBL6060987 | 0.95 | HIF1A (0.70) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150198913-A1 | TRANSFER ASSIST MEMBERS | XEROX CORPORATION (US) | 2015-07-16 | — | — | US | disclosed |
| US-9069294-B1 | Transfer assist members | XEROX CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| EP-2112134-B1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | SYNDROMEX LTD (IL) | 2013-10-30 | — | — | EP | disclosed |
| US-8129552-B2 | for transporting drugs or as gene transport vehicles, as solubilizers for drugs of low solubility in water, and themselves as active ingredients against diseases such as cancer or leishmaniosis; (Z)-6-octadecenyl-1-phospho-N,N,N-trimethylpropylammonium | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-03-06 | — | — | US | disclosed |
| EP-2112134-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | Syndromex Ltd. (IL) | 2009-10-28 | — | — | EP | disclosed |
| EP-0988274-B1 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNDROMEX LTD (IL) | 2009-05-20 | — | — | EP | disclosed |
| US-20080214849-A1 | PHOSPHOLIPIDS WITH UNSATURATED ALKYL AND ACYL CHAINS | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSHAFTEN E.V. (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20060229400-A1 | Powder coating matting agent comprising ester amide condensation product | FLETCHER TIM | 2006-10-12 | — | — | US | disclosed |
| US-20050288450-A1 | Coating matting agent comprising amide condensation product | FLETCHER TIM | 2005-12-29 | — | — | US | disclosed |
| EP-1509561-A1 | POWDER COATING MATTING AGENT COMPRISING ESTER AMIDE CONDENSATION PRODUCT | Grace GmbH & Co. KG (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20040132818-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | SYNDROMEX LTD. (IL) | 2004-07-08 | — | — | US | disclosed |
| WO-2003102048-A1 | POWDER COATING MATTING AGENT COMPRISING ESTER AMIDE CONDENSATION PRODUCT | GRACE GMBH & CO. KG (DE) | 2003-12-11 | — | — | WO | disclosed |
| US-20020049345-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | SYNDROMEX LTD. (IL) | 2002-04-25 | — | — | US | disclosed |
| EP-0780452-B1 | Aqueous paint | TOYO SEIKAN KAISHA LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6284903-B1 | TREATING HYPERLIPIDEMIA, OBESITY AND IMPAIRED GLUCOSE TOLERANCE/NONINSULIN DEPENDENT DIABETES MELLITUS WITHOUT ADVERSELY AFFECTING ENERGY METABOLISM | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-09-04 | — | — | US | disclosed |
| US-5763507-A | EPOXY ACRYLATE RESIN | TOYO SEIKAN KAISHA, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0780452-A2 | Aqueous paint | TOYO SEIKAN KAISHA LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5310854-A | Solvent, coatings for beverage cans | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| US-4933420-A | Epoxy resins containing phosphonium catalysts | THE DOW CHEMICAL COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0360195-A2 | Epoxy resins containing phosphonium catalysts | THE DOW CHEMICAL COMPANY (US) | 1990-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132818-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | CYP2F1, QPCT, CBR3 | HIF1A 1562/4885ALDH1A1 209/4885CYP1A2 300/4885 |
| US-20080214849-A1 | PHOSPHOLIPIDS WITH UNSATURATED ALKYL AND ACYL CHAINS | PHOSPHO1, PLTP, SGMS1 | HIF1A 4557/4885ALDH1A1 4394/4885CYP1A2 3227/4885 |
| US-20020049345-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | CYP2F1, QPCT, CYP2D6 | HIF1A 1474/4885ALDH1A1 206/4885CYP1A2 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.