Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441348 | 1.00 | MRGPRX4 (0.64) | MRGPRX4RAB9ANPC1S1PR5CYSLTR2 | |
| SCHEMBL10272647 | 0.88 | MRGPRX4 (0.64) | MRGPRX4RAB9ANPC1KCNH2NR4A1 | |
| SCHEMBL9441310 | 0.88 | MRGPRX4 (0.60) | MRGPRX4S1PR5CYSLTR2CYSLTR1KCNH2 | |
| SCHEMBL9441315 | 0.88 | MRGPRX4 (0.60) | MRGPRX4S1PR5CYSLTR2CYSLTR1KCNH2 | |
| SCHEMBL7369689 | 0.84 | MRGPRX4 (0.60) | MRGPRX4RAB9ANPC1KCNH2NR4A1 | |
| SCHEMBL7369690 | 0.84 | MRGPRX4 (0.60) | MRGPRX4RAB9ANPC1KCNH2NR4A1 | |
| SCHEMBL12523729 | 0.81 | MRGPRX4 (0.57) | MRGPRX4RAB9ANPC1KCNH2NR4A1 | |
| SCHEMBL12525375 | 0.81 | MRGPRX4 (0.57) | MRGPRX4RAB9AKCNH2LIPGHRH3 | |
| SCHEMBL27262322 | 0.81 | RAB9A (0.55) | MRGPRX4RAB9ANPC1CYSLTR2CYSLTR1 | |
| SCHEMBL5691491 | 0.81 | MAOB (0.62) | MRGPRX4RAB9AKCNH2LIPGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465048-B1 | Carboxylic acid ester compound, liquid crystal compound, liquid crystal composition, liquid crystal element and light modulation method | MITSUI PETROCHEMICAL IND (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5356561-A | Carboxylate compounds, liquid crystal compositions and liquid crystal elements containing said compounds and method of optical modulation using said elements | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0465048-A2 | Carboxylic acid ester compound, liquid crystal compound, liquid crystal composition, liquid crystal element and light modulation method | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |