SCHEMBL8999896

SCHEMBL8999896

C[Si](C)(CCCc1ccc(O)cc1)O[Si](C)(C)O[Si](C)(C)CCCc1ccc(O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.49
ESR1 P03372 5/20 0.47
ADRA2A P08913 3/20 0.47
SLC6A2 P23975 3/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
ADORA3 P0DMS8 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47
LMNA P02545 1/20 0.47
SHBG P04278 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
HSPD1 P10809 1/20 0.47
ADRB3 P13945 1/20 0.47
HTR2C P28335 1/20 0.47
HSPE1 P61604 1/20 0.47
HIF1A Q16665 1/20 0.47
TST Q16762 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8999952 0.98 CALM1 (0.47) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL8999904 0.98 CALM1 (0.47) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL8999888 0.93 CALM1 (0.52) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL12574830 0.89 CALM1 (0.49) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL13492505 0.88 CALM1 (0.41) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL8999982 0.87 ESR1 (0.53) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL14522310 0.86 CALM1 (0.46) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL10249606 0.86 ESR1 (0.58) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL12574836 0.83 ESR1 (0.53) CALM1ESR1ADRA2ASLC6A2KDM4E
SCHEMBL13492509 0.82 ESR1 (0.43) CALM1ESR1ADRA2ASLC6A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130172459-A1 PROCESS FOR PRODUCING COMPATIBILIZED RESIN, THERMOSETTING RESIN COMPOSITION, PREPREG, AND LAMINATE HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-07-04 US disclosed
US-5578697-A DIELECTRIC POLYMERS FOR ELECTRONICS KABUSHIKI KAISHA TOSHIBA (JP) 1996-11-26 US disclosed