Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999963 | 0.94 | TSHR (0.33) | TSHRMAPK1ESR1ESR2 | |
| SCHEMBL30891616 | 0.92 | TSHR (0.37) | TSHRMAPK1 | |
| SCHEMBL30891614 | 0.90 | TSHR (0.35) | TSHRMAPK1 | |
| SCHEMBL5185100 | 0.85 | TSHR (0.35) | TSHRMAPK1 | |
| SCHEMBL5185127 | 0.85 | TSHR (0.35) | TSHRMAPK1 | |
| SCHEMBL9000007 | 0.85 | TSHR (0.35) | TSHRMAPK1ESR1ESR2 | |
| SCHEMBL5186928 | 0.85 | TSHR (0.35) | TSHRMAPK1 | |
| SCHEMBL3869874 | 0.85 | TSHR (0.38) | TSHRMAPK1 | |
| SCHEMBL8999917 | 0.79 | TSHR (0.46) | TSHRMAPK1 | |
| SCHEMBL7184496 | 0.79 | TSHR (0.46) | TSHRMAPK1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578697-A | DIELECTRIC POLYMERS FOR ELECTRONICS | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-11-26 | — | — | US | disclosed |