Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194676 | 0.90 | KIF11 (0.50) | TSHRMAPK1PTPN5NR2E1KIF11 | |
| SCHEMBL8999898 | 0.89 | TSHR (0.42) | TSHRMAPK1PTPN5IDO1NR2E1 | |
| SCHEMBL130383 | 0.87 | TSHR (0.56) | TSHRMAPK1PTPN5IDO1NR2E1 | |
| SCHEMBL7186632 | 0.87 | TSHR (0.66) | TSHRMAPK1IDO1KIF11CES2 | |
| Iodide SCHEMBL31550893 | 0.85 | TSHR (0.54) | TSHRMAPK1PTPN5IDO1NR2E1 | |
| SCHEMBL9000007 | 0.84 | TSHR (0.35) | TSHRMAPK1ESR1ESR2 | |
| SCHEMBL7184500 | 0.82 | TSHR (0.38) | TSHRMAPK1PTPN5KIF11CES2 | |
| SCHEMBL394717 | 0.82 | TSHR (0.56) | TSHRMAPK1PTPN5IDO1NR2E1 | |
| SCHEMBL8999963 | 0.80 | TSHR (0.33) | TSHRMAPK1ESR1ESR2 | |
| SCHEMBL8999915 | 0.80 | TSHR (0.50) | TSHRMAPK1PTPN5IDO1NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-5578697-A | DIELECTRIC POLYMERS FOR ELECTRONICS | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-11-26 | — | — | US | disclosed |