SCHEMBL9000144

SCHEMBL9000144

CCOP(=O)(CS(=O)(=O)Cc1nc[nH]n1)OCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9000159 0.72 TSHR (0.35) TSHRPPARD
SCHEMBL9000115 0.71 TSHR (0.34) TSHRPPARD
SCHEMBL9961218 0.70 TSHR (0.52) TSHRPPARD
SCHEMBL8389801 0.69 MAPT (0.38) TSHRPPARD
SCHEMBL8762965 0.69 TSHR (0.32) TSHR
SCHEMBL9000152 0.69 TSHR (0.32) TSHR
SCHEMBL11207824 0.68 MAPT (0.32) TSHR
SCHEMBL11769516 0.67 KMT2A (0.44)
SCHEMBL21293353 0.65 AOC2 (0.31)
SCHEMBL159202 0.62 TSHR (0.52) TSHRPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730408-A1 TRIAZOLE PHOSPHONATE PESTICIDES AgrEvo UK Limited (GB) 1996-09-11 EP disclosed
WO-1995014385-A1 TRIAZOLE PHOSPHONATE PESTICIDES AGREVO UK LIMITED (GB) 1995-06-01 WO disclosed