Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871125 | 0.84 | MEN1 (0.49) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL11682423 | 0.84 | POLB (0.50) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL23718228 | 0.82 | MAPT (0.61) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL2223232 | 0.81 | MAPT (0.66) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL1715679 | 0.79 | POLB (0.68) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL8003873 | 0.78 | POLB (0.66) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL13597544 | 0.78 | SHMT2 (0.46) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL3131292 | 0.78 | POLB (0.66) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL4369241 | 0.77 | KMT2A (0.65) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL124721 | 0.76 | GAA (0.65) | MAPTKMT2AMEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036208-B2 | Methods for treating neurodegenerative disorders | ALZHEON, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12036208-B2 | Methods for treating neurodegenerative disorders | ALZHEON, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-11077095-B2 | Methods for treating neurodegenerative disorders | ALZHEON, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| EP-0445627-B1 | Silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0445627-A1 | Silver halide photographic light-sensitive materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4102688-A | CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY | FUJI PHOTO FILM CO., LTD. (JP) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077095-B2 | Methods for treating neurodegenerative disorders | NLN, CLN6, SNCA | MAPT 9/4885KMT2A 3467/4885MEN1 4000/4885 |
| US-12036208-B2 | Methods for treating neurodegenerative disorders | NLN, CLN6, SNCA | MAPT 9/4885KMT2A 3467/4885MEN1 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.