Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | CERT1 | Q9Y5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464125 | 0.98 | NR1I2 (0.44) | SIGMAR1NR1I2MMEHTR2AASAH1 | |
| SCHEMBL10780919 | 0.94 | MME (0.44) | SIGMAR1MMEHTR2AASAH1OPRM1 | |
| SCHEMBL7169115 | 0.88 | SIGMAR1 (0.47) | SIGMAR1NR1I2HTR2AOPRM1OPRD1 | |
| SCHEMBL6680917 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 | |
| SCHEMBL21633686 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 | |
| SCHEMBL23849703 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 | |
| SCHEMBL21633712 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 | |
| SCHEMBL21633771 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 | |
| SCHEMBL6681486 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 | |
| SCHEMBL20291563 | 0.86 | NR1I2 (0.49) | SIGMAR1NR1I2HTR2AASAH1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020068796-A9 | POLYCARBONATE BLOCK COPOLYMERS AND METHODS THEREOF | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2020-07-30 | — | — | WO | disclosed |
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |