Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000803 | 0.86 | SOAT1 (0.37) | SOAT1 | |
| SCHEMBL9000829 | 0.82 | SOAT1 (0.37) | SOAT1HPGDKDM4E | |
| SCHEMBL8325945 | 0.72 | SOAT1 (0.47) | SOAT1HPGDKDM4E | |
| SCHEMBL8326103 | 0.72 | SOAT1 (0.47) | SOAT1HPGDKDM4E | |
| SCHEMBL9000921 | 0.69 | SOAT1 (0.41) | SOAT1HPGD | |
| SCHEMBL9000483 | 0.69 | SOAT1 (0.41) | SOAT1HPGD | |
| SCHEMBL9000736 | 0.69 | SOAT1 (0.41) | SOAT1HPGD | |
| SCHEMBL9008152 | 0.69 | SOAT1 (0.36) | SOAT1KDM4E | |
| SCHEMBL8323636 | 0.68 | SOAT1 (0.38) | SOAT1 | |
| SCHEMBL4985295 | 0.68 | SOAT1 (0.50) | SOAT1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |