Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000614 | 0.90 | SOAT1 (0.38) | SOAT1 | |
| SCHEMBL9000682 | 0.86 | SOAT1 (0.40) | SOAT1 | |
| SCHEMBL9000515 | 0.86 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL9000830 | 0.78 | SOAT1 (0.39) | SOAT1 | |
| SCHEMBL9000550 | 0.74 | SORT1 (0.40) | SOAT1 | |
| SCHEMBL9000583 | 0.73 | KDM1A (0.37) | SOAT1 | |
| SCHEMBL32667998 | 0.72 | CYP1A2 (0.50) | SOAT1 | |
| SCHEMBL9000743 | 0.72 | SOAT1 (0.38) | SOAT1 | |
| SCHEMBL9000766 | 0.72 | SOAT1 (0.38) | SOAT1 | |
| SCHEMBL14565845 | 0.72 | SOAT1 (0.46) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |