Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265111 | 0.81 | TSHR (1.00) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL31384289 | 0.81 | TSHR (1.00) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL30471713 | 0.81 | TSHR (0.67) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL30471712 | 0.81 | TSHR (0.67) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL30540410 | 0.81 | TSHR (0.67) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL28929672 | 0.81 | TSHR (0.67) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL11410044 | 0.75 | TSHR (0.64) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL20945141 | 0.75 | TSHR (0.73) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL30471655 | 0.75 | TSHR (0.73) | TSHRMEN1KMT2APOLBPLEC | |
| SCHEMBL31037104 | 0.73 | TSHR (0.56) | TSHRMEN1KMT2APOLBPLEC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552298-A | Enzyme-catalyzed chemiluminescence from hydroxyaryl cyclic diacylhydrazide compounds | LUMIGEN, INC. (US) | 1996-09-03 | — | — | US | claimed |