Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000750 | 0.81 | KDM4E (0.57) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL6579453 | 0.80 | KDM4E (0.57) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL9000730 | 0.80 | DAO (0.37) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL8481568 | 0.78 | KMT2A (0.68) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL6579403 | 0.77 | KDM4E (0.53) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL6577224 | 0.75 | KDM4E (0.66) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 | |
| SCHEMBL6579858 | 0.72 | KDM4E (0.57) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9341752 | 0.70 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6579272 | 0.70 | KDM4E (0.59) | KDM4EALDH1A1MAPTPOLBIDE | |
| SCHEMBL10018546 | 0.69 | KDM4E (0.62) | KDM4EKMT2AMEN1SMN1; SMN2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544152-B1 | Herbicidal quinoline-3-carbonamides | BASF AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| EP-0544152-A1 | Herbicidal quinoline-3-carbonamides | BASF Aktiengesellschaft (DE) | 1993-06-02 | — | — | EP | disclosed |