Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16311011 | 0.86 | TRPA1 (0.41) | PDK2TRPA1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29683736 | 0.81 | PDK2 (0.51) | PDK2TRPA1ALDH1A1MAPTMAPK1 | |
| SCHEMBL899538 | 0.81 | ESR1 (0.60) | PDK2TRPA1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL900437 | 0.81 | TRPA1 (0.44) | PDK2TRPA1ALDH1A1MAPTMAPK1 | |
| SCHEMBL899485 | 0.80 | PDK2 (0.47) | PDK2TRPA1ALDH1A1MAPTMAPK1 | |
| SCHEMBL31633741 | 0.79 | PDE4D (0.50) | PDK2PDE4DMAPTMEN1KMT2A | |
| SCHEMBL900053 | 0.77 | CNR1 (0.54) | PDK2TRPA1PDE4DALDH1A1ALOX15 | |
| SCHEMBL899918 | 0.76 | PDK2 (0.43) | PDK2TRPA1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7050088 | 0.76 | MAPT (0.65) | PDK2ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL29579551 | 0.76 | MAPT (0.65) | PDK2ALDH1A1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042058-A1 | IMPACT RESISTANCE MODIFIERS FOR EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2012-04-05 | — | — | WO | disclosed |