Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655589 | 0.81 | ALDH1A1 (0.46) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL3641246 | 0.75 | ALDH1A1 (0.43) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL3163357 | 0.71 | ALDH1A1 (0.39) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL11524279 | 0.70 | ALDH1A1 (0.39) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL1725501 | 0.69 | TSHR (0.39) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL2132797 | 0.66 | ALDH1A1 (0.36) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL11798471 | 0.66 | TSHR (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3151180 | 0.66 | ALDH1A1 (0.38) | ALDH1A1POLBL3MBTL1MAPTTP53 | |
| SCHEMBL1536093 | 0.65 | ALDH1A1 (0.54) | ALDH1A1POLBL3MBTL1MAPTTLR4 | |
| SCHEMBL28438080 | 0.65 | ALDH1A1 (0.60) | ALDH1A1POLBL3MBTL1MAPTTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481034-A | STABILITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-01-02 | — | — | US | disclosed |