Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900028 | 0.84 | ESR1 (0.45) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL13910138 | 0.81 | TNFRSF1A (0.35) | ALDH1A1PTGS1PTGS2PDK2EGFR | |
| SCHEMBL899918 | 0.80 | PDK2 (0.43) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL900101 | 0.80 | ESR1 (0.50) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL899618 | 0.80 | ESR1 (0.45) | CA2ALDH1A1PTGS1PTGS2CA1 | |
| SCHEMBL900053 | 0.74 | CNR1 (0.54) | CA2ALDH1A1CA1PDK2ALOX15 | |
| SCHEMBL19750291 | 0.73 | PDK2 (0.42) | CA2SMN1; SMN2CA1PDK2MEN1 | |
| SCHEMBL19286810 | 0.72 | PDK2 (0.47) | CA2SMN1; SMN2ALDH1A1CA1PDK2 | |
| SCHEMBL12374333 | 0.72 | PDK2 (0.38) | POLBPDK2TSHR | |
| SCHEMBL12963010 | 0.71 | PKM (0.48) | PDK2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042058-A1 | IMPACT RESISTANCE MODIFIERS FOR EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2012-04-05 | — | — | WO | disclosed |