Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001934 | 0.83 | GAA (0.51) | RAB9ASMN1; SMN2 | |
| SCHEMBL9002337 | 0.83 | SMN1; SMN2 (0.38) | TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9002424 | 0.80 | CDK8 (0.37) | ALDH1A1 | |
| SCHEMBL9001944 | 0.76 | MAPK1 (0.43) | TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9002014 | 0.74 | CYP1A2 (0.35) | TP53RAB9AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9001928 | 0.74 | CDK8 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9001997 | 0.71 | CHEK1 (0.30) | — | |
| SCHEMBL9002046 | 0.71 | MAP4K2 (0.32) | TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9002232 | 0.69 | CDK8 (0.37) | RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7835501 | 0.69 | SMN1; SMN2 (0.35) | TP53RAB9AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |