Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738562 | 0.84 | TSHR (0.33) | P2RX7ALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL29523337 | 0.82 | ACP3 (0.46) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL6564259 | 0.82 | ACP3 (0.46) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL10540798 | 0.80 | ACP3 (0.44) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL9864039 | 0.78 | ACP3 (0.47) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL15129454 | 0.77 | ACP3 (0.42) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL29052941 | 0.77 | ACP3 (0.54) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL10546400 | 0.75 | ACP3 (0.47) | ACP3P2RX7CNR2HSD11B1IDO1 | |
| SCHEMBL3987454 | 0.74 | GABRA1 (0.46) | ALDH1A1POLBTDP1L3MBTL1KDM4E | |
| SCHEMBL308175 | 0.74 | ACP3 (0.47) | ACP3P2RX7CNR2HSD11B1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731790-A1 | TACHYKININ ANTAGONISTS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1996-09-18 | — | — | EP | disclosed |