Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002922 | 0.98 | KMT2A (0.42) | KMT2APOLBEPHX2NOD1MMEL1 | |
| SCHEMBL7394796 | 0.88 | KMT2A (0.40) | KMT2APOLBNOD1MEN1FAAH | |
| SCHEMBL7395604 | 0.85 | KMT2A (0.39) | KMT2APOLBNOD1L3MBTL1GAA | |
| SCHEMBL8719543 | 0.76 | CYP1A2 (0.44) | — | |
| SCHEMBL8721817 | 0.75 | CYP1A2 (0.43) | — | |
| SCHEMBL8019564 | 0.74 | KMT2A (0.60) | KMT2APOLBEPHX2NOD1PLA2G2C | |
| SCHEMBL8019568 | 0.74 | KMT2A (0.60) | KMT2APOLBEPHX2NOD1PLA2G2C | |
| SCHEMBL9002996 | 0.72 | MEN1 (0.41) | KMT2APOLBMMEL1MEN1L3MBTL1 | |
| SCHEMBL8019574 | 0.71 | NOD1 (0.60) | KMT2APOLBEPHX2NOD1MEN1 | |
| SCHEMBL8018791 | 0.70 | NOD1 (0.55) | KMT2AEPHX2NOD1PLA2G2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |