Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 10/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4444508 | 0.97 | BBOX1 (0.54) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL4444511 | 0.88 | BBOX1 (0.52) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Acetic Acid SCHEMBL5844598 | 0.88 | BBOX1 (0.52) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL30381501 | 0.88 | BBOX1 (0.52) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL1051688 | 0.88 | BBOX1 (0.52) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Propionic Acid SCHEMBL11436115 | 0.85 | BBOX1 (0.56) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL9003742 | 0.84 | BBOX1 (0.42) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Oxalic Acid SCHEMBL1051691 | 0.82 | BBOX1 (0.48) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL8995782 | 0.81 | BBOX1 (0.52) | BBOX1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL10641701 | 0.80 | BBOX1 (0.46) | BBOX1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538832-A | Developing solution for producing printed circuit boards and a process for producing printed circuit boards wherein the developing solution comprises a quaternary ammonium hydroxide and a quaternary ammonium carbonate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1996-07-23 | — | — | US | disclosed |