Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GLUL | P15104 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003529 | 1.00 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL9003604 | 1.00 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL9003813 | 0.78 | CYP2D6 (0.44) | — | |
| SCHEMBL9003822 | 0.78 | CYP2D6 (0.44) | — | |
| SCHEMBL10212363 | 0.76 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL21585639 | 0.76 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL21690060 | 0.76 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL21577845 | 0.76 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL434919 | 0.76 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 | |
| SCHEMBL434918 | 0.76 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC1A1SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500419-A | NMDA antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-03-19 | — | — | US | disclosed |