SCHEMBL9003585

SCHEMBL9003585

O=[S+]Cc1cccc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 2/20 0.37
PTGS1 P23219 1/20 0.37
SUCNR1 Q9BXA5 2/20 0.34
AHR P35869 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
FFAR4 Q5NUL3 2/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
FFAR1 O14842 1/20 0.34
NR4A2 P43354 1/20 0.33
CYP1A2 P05177 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
GCG P01275 1/20 0.31
HTR7 P34969 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003531 0.84 DPP4 (0.42) ADORA2AADORA1ALDH1A1MAPTHTR7
SCHEMBL2389062 0.79 NR4A2 (0.44) CYP2C19PTGS2PTGS1SUCNR1SLC6A4
SCHEMBL9239435 0.75 CYP1A2 (0.48) PTGS2PTGS1AHRSLC6A4SLC6A3
SCHEMBL25644772 0.70 CYP1A2 (0.61) PTGS2PTGS1SLC6A4SLC6A3ADORA2A
SCHEMBL11151198 0.70 CYP1A2 (0.61) PTGS2PTGS1SLC6A4SLC6A3ADORA2A
SCHEMBL4328698 0.67 NPC1 (0.46) CYP2C19PTGS2PTGS1SLC6A4SLC6A3
SCHEMBL6930595 0.67 CYP1A2 (0.39) PTGS2PTGS1AHRSLC6A4SLC6A3
SCHEMBL6350642 0.67 PTGS2 (0.43) PTGS2PTGS1SLC6A3ADORA2AADORA1
SCHEMBL10058354 0.67 PTGS2 (0.52) CYP2C19PTGS2PTGS1SUCNR1SLC6A4
SCHEMBL2870886 0.67 PTGS2 (0.40) CYP2C19PTGS2PTGS1AHRSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500453-A INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-19 US disclosed