Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586309 | 0.88 | IDO1 (0.46) | IDO1 | |
| SCHEMBL543414 | 0.88 | IDO1 (0.46) | IDO1 | |
| SCHEMBL4847731 | 0.81 | IDO1 (0.42) | IDO1BLMADRA2AADRA1ACYP2D6 | |
| SCHEMBL20706323 | 0.81 | IDO1 (0.49) | IDO1ADRA2AADRA1ACYP2D6LMNA | |
| SCHEMBL297121 | 0.79 | IDO1 (0.41) | IDO1BLMADRA2AADRA1ACYP2D6 | |
| SCHEMBL22808450 | 0.78 | IDO1 (0.50) | IDO1LMNAHTTALDH1A1 | |
| SCHEMBL14815564 | 0.78 | IDO1 (0.46) | IDO1LMNAHTTALDH1A1 | |
| SCHEMBL10836441 | 0.77 | IDO1 (0.45) | IDO1BLMTSHRHTTALDH1A1 | |
| SCHEMBL30276343 | 0.76 | HTT (0.51) | TSHRLMNAHTTALDH1A1MEN1 | |
| SCHEMBL11141197 | 0.75 | PNMT (0.42) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414686-B1 | DERIVATIVES OF TRIFLUOROMETHYL-1-TETRALINES, PREPARATION AND APPLICATION THEREOF FOR THE SYNTHESIS OF COMPOUNDS HAVING THERAPEUTIC PROPERTIES | LABORATOIRES LUCIEN (FR) | 1993-09-22 | — | — | EP | claimed |
| US-7648651-B2 | Solvent composition | ADEKA CORPORATION (JP) | 2010-01-19 | — | — | US | disclosed |
| US-7648651-B2 | Solvent composition | ADEKA CORPORATION (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20090093588-A1 | Solvent Composition | ADEKA CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20090093588-A1 | Solvent Composition | ADEKA CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-5490986-A | SYNTHETIC BLOOD | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1996-02-13 | — | — | US | disclosed |
| US-5284663-A | Artificial blood substitute; Lewis acid-Lewis base salt with perfluorocarbon encapsulated therein | TEMPLE UNIVERSITY (US) | 1994-02-08 | — | — | US | disclosed |
| WO-1993001806-A1 | ENCAPSULATED PERFLUOROCARBONS | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-02-04 | — | — | WO | disclosed |