Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459872 | 0.93 | GABRP (0.54) | RARBRXRAGABRPGABRDGABRA1 | |
| Oxalic Acid SCHEMBL28508104 | 0.90 | GABRP (0.51) | RARBRXRAGABRPGABRDGABRA1 | |
| SCHEMBL7934928 | 0.88 | RARB (0.54) | RARBTP53TSHRMEN1ALDH1A1 | |
| SCHEMBL8516008 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL8515505 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL7262506 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL7264156 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL7263380 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL7271225 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL3459040 | 0.87 | PPARA (0.56) | RARBTP53TSHRPLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733037-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015941-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1995-06-15 | — | — | WO | disclosed |